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In an embodiment, the 7,9-substituted tetracycline compound is 7,9-substituted tetracycline (eg, wherein R 4 is NR 4′R 4″; R 4′ and R 4″ are methyl, R 5 is hydrogen and X is CR 6R 6′, wherein R 6 is methyl and R 6′ is hydroxy); 7,9-substituted doxycycline (eg, wherein R 4 is NR 4′R 4″; R 4′ and R 4″ are methyl, R 5 is hydroxyl and X is CR 6R 6′, wherein R 6 is methyl and R 6′ is hydrogen); or 7,9-substituted sancycline (wherein R 4 is NR 4′R 4″; R 4′ and R 4″ are methyl; R 5 is hydrogen and X is CR 6R 6′ wherein R 6 and R 6′ are hydrogen atoms. Dadurch wird auch die Ausscheidung von Kalium, actonel generic price Protonen (H+) und Wasser gesteigert? Other derivatives and analogues comprising a similar four ring structure are also included?

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